(S) N-glycidyl phthalimide, commonly referred to as (S) - N-PiP ((S) - N-phenylpyrrole-2-carboxamide
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(S) N-glycidyl phthalimide, commonly referred to as (S) - N-PiP ((S) - N-phenylpyrrole-2-carboxamide).
nature :
(S) N-glycidyl phthalimide is an organic compound. It is a colorless to light yellow crystal that is soluble in common organic solvents such as dimethyl sulfoxide and dichloromethane.
Objectif :
(S) N-glycidyl phthalimide is widely used in chiral organic synthesis as a precursor for chiral catalysts or ligands. It can be used for asymmetric synthesis reactions, such as asymmetric addition and asymmetric dehydration.
Méthode de fabrication :
(S) The preparation of N-glycidol phthalimide is usually achieved by first synthesizing (S) - N-glycidol ((S) - N-proline) and then reacting it with phthalimide. The specific preparation method can refer to relevant organic synthesis literature.
Informations de sécurité :
(S) There are currently few reports on the safety information of N-glycidyl phthalimide, but as an organic compound, the following safety measures should generally be taken:
-Avoid contact with skin, eyes, or respiratory tract, and wear appropriate protective gloves, glasses, and masks.
-During the operation, it is necessary to prevent the generation of dust, smoke, or gas and maintain well ventilated laboratory conditions.
-Store in a dry and cool place, away from sources of fire and oxidants.
-Follow proper handling and disposal procedures to avoid harm to the environment.
Nom | (S)-(+)-Glycidyl Phthalimide |
Synonymes | Rivaroxaban Impurity 39 (S)-Glycidyl Phthalimide (S)-GLYCIDYL PHTHALIMIDE (S)-N-Glycidylphthalimide Diethyl (3-pyridyl) borane N-(S)-Glycidylphthalimide (S)-(+)-Glycidyl Phthalimide (S)-(+)-GLYCIDYL PHTHALIMIDE (S)-(+)-Glycidyl phthalimide (S)-(+)-N-(2,3-Epoxypropyl)phthalimide (S)-2-oxiranylmethyl-isoindole-1,3-dione (S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione 2-((2S)-oxiranylmethyl)-1H-isoindole-1,3(2H)-dione 2-((2S)-OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE 2-[(2S)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]- |
CAS | 161596-47-0 |
EINECS | 1308068-626-2 |
InChI | InChI=1/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1 |
Formule moléculaire | C11H9NO3 |
Masse molaire | 203.19 |
Densité | 1.446±0.06 g/cm3(Predicted) |
Point de fusion | 102 °C |
point Boling | 347.4±15.0 °C(Predicted) |
Point d'éclair | 163.9°C |
Solubilité | Chloroform (Slightly), Ethyl Acetate (Slightly) |
pression vapeur | 0.001-2.17Pa at 25-90.25℃ |
Apparence | White powder |
Couleur | blanc |
Le PKA | -2.24±0.20(Predicted) |
Condition de stockage | sous gaz inerte (azote ou argon) à 2-8°C |
Sensible | Facile à absorber l'humidité |
Indice de réfraction | 10 ° (C=2.2, CHCl3) |
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