5-Bromo-8-methoxy-2-methylquinoline CAS 103862-55-1

5-Bromo-8-methoxy-2-methylquinoline - Names and Identifiers

Nom	5-Bromo-8-methoxy-2-methylquinoline
Synonymes	ZINC02534104 5-Bromo-8-methoxy-2-methylquinoline 5-Bromo-6-Methoxy-2-methylquinoline 5-bromo-8-methoxy-2-methyl-quinoline 5-BROMO-8-METHOXY-2-METHYL-QUINOLINE Quinoline, 5-bromo-8-methoxy-2-methyl-
CAS	103862-55-1
InChI	InChI=1S/C11H10BrNO/c1-7-3-4-8-9(12)5-6-10(14-2)11(8)13-7/h3-6H,1-2H3

5-Bromo-8-methoxy-2-methylquinoline - Physico-chemical Properties

Formule moléculaire	C11H10BrNO
Masse molaire	252.11
Densité	1.455
Point de fusion	114℃
point Boling	341℃
Point d'éclair	160℃
Le PKA	3.01±0.50(Predicted)
Condition de stockage	Scellé à sec, température ambiante

5-Bromo-8-methoxy-2-methylquinoline - Introduction

5-Bromo-8-methoxy-2-methylquinoline is an organic compound. Its molecular formula is C12H12BrNO, and the structural formula is as follows:

Br
|
OCH3
|
CH3

C
//
HN C
\
CH3

The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature :
1. Aspect: solide cristallin blanc.
2. Melting point: about 60-62°C.
3. Boiling point: about 211-212°C.
4. Solubility: limited solubility in water, soluble in organic solvents such as ethanol and dichloromethane.

Utilisation:
1. 5-Bromo-8-methoxy-2-methylquinoline is often used as a pharmaceutical intermediate for the synthesis and research of other compounds.
2. It can be used to synthesize biologically active molecules, such as anti-tumor drugs.

Méthode de préparation :
There are many preparation methods of 5-bromo-8-methoxy-2-methylquinoline, one of which is a common method of synthesis through the following steps:
1. Methoxyacetic anhydride reacts with 2-methyl quinoline to generate 2-amino -8-methoxyquinoline.
2. reacting 2-amino -8-methoxyquinoline with bromoacetic acid to generate 5-bromo -8-methoxy -2-methyl quinoline.

Informations sur la sécurité :
1. 5-Bromo-8-methoxy-2-methylquinoline is an organic compound, which should be used in accordance with laboratory safety procedures.
2. The compound may be irritating to the eyes, skin and respiratory tract, and direct contact should be avoided.
3. during use or storage, it should be kept in a cool, dry, well-ventilated place, and avoid contact with flammable substances.
4. Waste should be disposed of according to local regulations and should not be inverted at will.