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Fmoc-D-Glu(OtBu)-OH CAS 104091-08-9

Fmoc-D-Glu(OtBu)-OH - Names and IdentifiersNameFmoc-D-Glu(OtBu)-OHSynonymsFMOC-D-GLU(TBU)-OHFmo

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Fmoc-D-Glu(OtBu)-OH - Names and Identifiers

NomFmoc-D-Glu(OtBu)-OH
SynonymesFMOC-D-GLU(TBU)-OH
Fmoc-D-Glu(OBut)-OH
Fmoc-D-Glu(OtBu)-OH
quinoline-6-carbaldehyde
FMOC-D-GLUTAMIC ACID(O-T-BUTYL)
Fmoc-D-glutamic acid 5-tert-butyl ester
N-Fmoc-D-glutamic acid 5-tert-butyl ester
Fmoc-D-glutamic acid gamma-tert-butyl ester
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-GLUTAMIC-ACID-GAMMA-T-BUTYL ESTER
N-alpha-(9-fluorenylmethyloxycarbonyl)-D-glutamic-acid-gamma-t-butyl ester
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER MONOHYDRATE
(2R)-5-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
CAS104091-08-9
EINECS2017-001-1
InChIInChI=1/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m1/s1

Fmoc-D-Glu(OtBu)-OH - Physico-chemical Properties

Formule moléculaireC24H27NO6
Masse molaire425.47
Densité1.232±0.06 g/cm3(Predicted)
Point de fusion83-89°C
point Boling633.5±55.0 °C(Predicted)
Point d'éclair336.9°C
Solubilité dans l'eauLégèrement soluble dans l'eau.
pression vapeur6.39E-17mmHg at 25°C
ApparenceSolide
CouleurBlanc à presque blanc
Le PKA3.70±0.10(Predicted)
Condition de stockage2 - 8 degrés Celsius
Indice de réfraction1.57
MDLMFCD00077055

Fmoc-D-Glu(OtBu)-OH - Risk and Safety

Description de la sécurité24/25 - Avoid contact with skin and eyes.
Wgk Allemagne3
Code SH2924 29 70

Fmoc-D-Glu(OtBu)-OH - Introduction

Fmoc-D-glutamic acid gamma-tert-butyl ester is an organic compound. Its chemical structure contains Fmoc protecting group, D-glutamic acid and gamma-tert-butyl ester group.

Nature :
Fmoc-D-glutamic acid gamma-tert-butyl ester is a white solid with a high melting point and solubility. It is relatively stable at room temperature, but will gradually hydrolyze in a humid environment.

Utilisation:
Fmoc-D-glutamic acid gamma-tert-butyl ester is mainly used in the field of peptide synthesis as a raw material for synthetic peptides. The Fmoc protecting group can protect the amino and carboxyl groups of glutamic acid from interference during the reaction. The tert-butyl ester group can provide convenient reaction conditions and a protecting group that can be easily removed.

Méthode de préparation :
The preparation of Fmoc-D-glutamic acid gamma-tert-butyl ester is usually carried out by a chemical synthesis method. Specifically, D-glutamic acid is first reacted with gamma-tert-butyl ester to form the target product under appropriate conditions. Then, an Fmoc protecting group was introduced into the product, and finally Fmoc-D-glutamic acid gamma-tert-butyl ester was obtained.

Informations sur la sécurité :
Fmoc-D-glutamic acid gamma-tert-butyl ester is generally safe to handle. However, as an organic compound, it may cause irritation to the skin, eyes and respiratory system. Therefore, appropriate safety measures should be taken during use, such as wearing gloves, goggles and masks, and maintaining good ventilation conditions. In addition, it is recommended to operate in a suitable laboratory environment and follow relevant safety and operating procedures. If an accident occurs, seek medical help immediately.

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