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Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylateCAS: 161798-01-2Appearance: y

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Contenu

Molecular Formula: C14H13NO4S Molecular Weight: 291.32 CAS Registry Number: 161798-01-2 Density: 1.3352- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester, also known as Ugi key intermediate, has the following properties and uses:

Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

CAS: 161798-01-2

Appearance: yellowish powder

Assay: ≥99%

Capacity: 100mt/year

Min.package: 1gram

Application: Febuxostat intermediate

Standard: enterprise export

nature :

Appearance: White crystalline powder

Soluble: soluble in some organic solvents such as methanol, ethanol, and dimethylformamide

Stability: Stable, not easily decomposed

Objectif :

Méthode de fabrication :

Ethyl 2- (3-aldehyde-4-hydroxyphenyl) -4-methylthiazole-5-carboxylate can be synthesized through a multi-step reaction. A common method is to react 3-hydroxy-4-methylbenzaldehyde with ethyl methoxyacetic acid, methyl mercaptan, and dimethylformamide, and obtain the target product after acid catalysis and deprotection reaction.

Informations de sécurité :

2- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester is a chemical with certain toxicity. Please pay attention to safety when using it.

When stored, it should be sealed and kept away from sources of fire and oxidants.

When preparing and using, relevant safety operating procedures and laboratory regulations should be followed, and personal protective equipment such as laboratory gloves and protective goggles should be used.

NomEthyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
SynonymesFebuxostat-23
5-carboxylato-1-ethyl-2-(3-forMyl-4-h
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl-5-Thiazolecarboxylate
Ethyl 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester
2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester
(2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester
CAS161798-01-2
EINECS692-179-2
InChIInChI=1/C14H13NO4S/c1-3-19-14(18)12-8(2)15-13(20-12)9-4-5-11(17)10(6-9)7-16/h4-7,17H,3H2,1-2H3
Formule moléculaireC14H13NO4S
Masse molaire291.32
Densité1.335
Point de fusion116 °C
point Boling446.7±55.0 °C(Predicted)
SolubilitéDiméthylsulfoxyde (léger), méthanol (léger)
ApparenceSolide
CouleurPale Yellow to Yellow
Le PKA6.81±0.20(Predicted)
Condition de stockagesous gaz inerte (azote ou argon) à 2-8°C
Indice de réfraction1.625

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