Bicalutamide

Molecular Formula: C18H14F4N2O4S Molecular Weight: 430.37 CAS No.: 90357-06-5 It is a non steroidal androgen antagonist, competing with androgen for androgen receptor, blocking the uptake of androgen by cells and inhibiting the binding of androgen with target organs. After binding with chemicalbook androgen receptor, it forms a receptor complex, enters the cell nucleus and binds with nucleoprotein, thereby inhibiting the growth of tumor cells; It can be used as a first-line drug for palliative treatment of advanced prostate cancer. Description It is a fine white to off white powder. It is practically insoluble in water at 37°C, slightly soluble in chloroform and absolute ethanol, sparingly soluble in methanol, and soluble in acetone and tetrahydrofuran. The pKa' is approximately 12. Application Antiandrogen drugs are used to treat advanced prostate cancer. Packing and Storage Preserve in tight containers. Store at room temperature. Minimum Order One package

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