Isoniazide

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Molecular Formula： C6H7N3O

Molecular Weight： 137.1

CAS No.: 54-85-3

It has strong antibacterial to bactericidal effects on Mycobacterium tuberculosis, and also acts on intracellular bacilli; Low toxicity, easy absorption, strong penetrability, used for various types of tuberculosis; It is easy to produce drug resistance when used alone, and it is often used with p-aminosalicylate or streptomycin.

Description

White or off white crystalline powder, odorless, slightly sweet and bitter after taste, with light gradient. Mp171.4℃. 1% aqueous solution ph5.5-6.5. The solution is stable at ph4cchemicalbook-5. It is easy to decompose in neutral or alkaline solutions, and the decomposition is accelerated by light, heat and oxygen. This product is easily soluble in water (1:10), soluble in ethanol (1:50), and insoluble in ether.

Application

It is highly sensitive to Mycobacterium tuberculosis, has certain effects on other gram-negative bacilli, and has strong antibacterial effect on Gram-positive cocci (including drug-resistant staphylococcus aureus). Chemicalbook Mycobacterium tuberculosis is easy to develop drug resistance to this product, and it often needs combined medication. Clinically, it is used to treat all types of tuberculosis, drug-resistant staphylococcus aureus infection, trachoma, leprosy and so on.

Packing and Storage    

Preserve in tight, light-resistant containers. Store at 25°C, excursions permitted between 15°C and 30°C.

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